Human Intrinsically Disordered Protein Interactions

The IDPpi_tool is a sequence-based web tool for PPI predictions for set of Human Intrinsically Disordered Proteins.

The dataset for benchmarking can be downloaded here.

Quick start guide

Select disorder protein of interest, from combo-box, or you can input your custom sequence of the disorder protein in FASTA format. Enter in the input box "Sequences" list of sequences in FASTA format. Click on the button "Send" and wait for the result. Predictions will be made for all combinations of selected disorder protein with each protein given in the the "Sequences" box.

Maximum number of sequences/interactions is 100.

Output

IDPpi_tool output is a real value that quantifies the probability of a given pair to form an interaction. Pairs with probabilities > 0.5 are assumed to form interaction.

Result in the summary table can be sorted by the probabilities in descending order, by checking the box "Sort result by p1 predicted values".