Parkinson’s disease (PD) is a neurodegenerative disorder with motor and non-motor symptoms related to dopaminergic loss. This project compares two innovative neuromodulatory therapies: the non-invasive SAINT protocol and the invasive burst DBS in a 6-OHDA rat model. Using behavioral, neurochemical and synaptic analyses, Serbian and Canadian teams will evaluate their efficacy and mechanisms. This collaboration will pioneer translational insights and optimize PD treatments and therapeutic outcomes.
