The Laboratory for radioisotopes of the Vinca Institute is a unique and modern scientific laboratory in the region, for the development, production and quality control of radioactive drugs-radiopharmaceuticals. It is registered by the Ministry of Health of the Republic of Serbia for the production of radiopharmaceuticals in accordance with Good Manufacturing Practice (GMP production). All radiopharmaceuticals are registered in accordance with EU regulations in the Agency for Medicines of the Republic of Serbia. Vinca's radiopharmaceuticals are the result of multidisciplinary research and are of inestimable value to thousands of patients per year who receive them during various diagnostic and therapeutic procedures in all clinical centers in Serbia and Republika of Srpska.

The specificity and quality of Vinca's radiopharmaceuticals is personalized therapy, i.e. a strictly individual approach to each patient, because an appropriate dose of radiopharmaceuticals is determined and prepared for each patient based on his condition, type and course of the disease.

Vinca’s Universal 99Mo/99mTc generator for obtaining the radionuclide technetium-99m, which in the form of a complex with various compounds enables sensitive and specific diagnosis and prediction of the course of a large number of diseases, including the most common, malignant ones and myocardial infarction, is celebrating 40 years of successful clinical applications. Therapeutic radiopharmaceuticals, radioactive 131I capsules, are indispensable in the treatment of hyperthyroidism and thyroid cancer, as well as 177Lu labeled peptides used in the treatment of neuroendocrine tumors.

In addition, the Laboratory plays an important role in the industry, as it replaces sealed radioactive sources in devices used to examine internal defects in metals, devices for measuring the level of explosive liquids and liquids under the high pressure in chemical reactors, and devices for radiotherapy in medical centres and thus allows users, in addition to significant savings, unlimited use of the device, as well as safe work in accordance with their needs.

The Laboratory for radioisotope is the only one in the Republic of Serbia that has licenses for high-risk radiation activities for the production of radiopharmaceuticals for use in medicine, the production, repackaging and recycling of sealed radioactive sources that are used in industry, as well as scientific research activities with open and closed radiation sources.

Products of the Laboratory for radioisotopes for use in medicine

Radioactive drugs - Radiopharmaceuticals

• ¹³¹I capsules for therapy
• ⁹⁹Mo/^99mTc Generator

Radiopharmaceutical kits for preparing of ^99mTc radiopharmaceuticals:

• ^99mTc-DPD
• ^99mTc-MIBI (sestamibi)
• ^99mTc(III)-DMSA (succimer)
• ^99mTc(V)-DMSA
• ^99mTc-DTPA (pentetate)
• ^99mTc-MAA (aggregate HSA)
• ^99mTc-Sn-colloid (tin colloid)
• ^99mTc- antimony-sulphide colloid
• ^99mTc-PYP (pyrophosphate)
• ^99mTc-EHIDA
• ^99mTc-ciprofloxacin

Services for the medicine and industry

• Radiolabeling of various compounds with radioisotopes for preclinical and clinical trials;
• Replacement of sealed radioactive sources in devices used in industry and medicine 
  • ⁶⁰Co source used for therapeutic purposes in clinical centres (radiotherapy, brachytherapy) as well as servicing of brachytherapy devices,
  • ¹⁹²Ir and ⁷⁵Se sources in radiographic devices for the application in industrial radiography,
  • ¹³⁷Cs and ⁶⁰Co sources for the process control in industrial plants,
  • ²⁴¹Am and ⁸⁵Kr sources for the needs of the paper industry, polyester foils, metal foils, tapes and sheets,
  • ²⁴¹Am-Be neutron sources for the needs of geophysical logging tests, as well as
  • dismantling of radioactive sources ⁶⁰Co and ^152,154Eu from radioactive lightning rods,
  • transport of radioactive sources on the territory of the Republic of Serbia in accordance with ADR regulations.

Laboratory contact information

Name of the organizational unit: Laboratory for radioisotopes
OU Number: 070
Head of OU: dr Sanja Vranješ-Đurić, Research Professor
e-mail: l.070@vinca.rs
Phone: 011 6308436
OU website: www.radioizotopi.rs