P2X receptors (P2XRs) are ATP-gated ion channels involved in intercellular communication with an established role in neurodegeneration, infection, inflammation, cancer growth, and progression. In vitro and in vivo evidence, generated mainly by leading Europe-based laboratories, shows that P2XRs might be an ideal pharmacological target in these diseases and many others. Over the years...
Fats and oils, which are collectively known as lipids, are very important substances in the body. They are largely taken in through the diet but several, like cholesterol, are also made in the body. They are critical components of the membranes that define the cells and the organelles inside them. They are transported around the body in lipoproteins such as LDL and HDL, and stored in...
Recent experiments with high-intensity lasers have shown record production of alpha particles by irradiating boron-hydrogen targets. This opens the way to completely new studies on pB fusion with multiple goals:
studies related to nuclear fusion. The proton-boron fusion reaction produces 3 a-particles and releases a large energy. It is considered an interesting alternative to ...The European Union (EU) has set an ambitious goal towards decarbonising energy production and achieving key climate change related objectives by 2030/2050. Photovoltaic (PV) solar cell (SC) technologies have already made significant progress and are on track towards meeting more than 5% of global energy demand by 2025. Moving forwards PV is recognized as one of the key renewable ener...
The COST Action TEATIME aims to develop and use automated home-cage monitoring technologies, combining experts in mouse behavior, laboratory animal science and data science, to critically and transparently assess the potential of these technologies, to develop user guidelines and standard operating procedures and to identify needs for further technological development, including anal...
the list of research instruments
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